"Translational Research in Cancer" ed. by Sivapatham Sundaresan, Yeun-Hwa Gu

The key features of the book include: 1) New screening for the development of radioprotectors: radioprotection and anti-cancer effect of β-Glucan (Enterococcus faecalis); 2) Translational perspective on hepatocellular carcinoma; 3) Brachytherapy for endometrial cancer; 4) Discovery of small molecule inhibitors for histone methyltransferases in cancer

Translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies concerning the molecular pathways involved in tumorigenesis. Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. The vast majority of cancer cases are due to environmental risk factors. Many of these environmental factors are controllable lifestyle choices. Experimental cancer treatments are studied in clinical trials to compare the proposed treatment to the best existing treatment through translational research.

Contents
1. Discovery of Small Molecule Inhibitors for Histone Methyltransferases in Cancer
2. IL10 as Cancer Biomarker
3. Ion Channels and Transporters as Cancer Biomarkers and Targets for Diagnostics with Antibodies
4. Translational Perspective in Hepatocellular Carcinoma
5. Chalcones: Potential Anticancer Agents
6. New Screening for the Development of Radioprotectors: Radioprotection and Anti-Cancer Effect of β-Glucan (Enterococcus faecalis)
7. Evaluation by Monte Carlo Simulation of Doses Distribution in Tumors with Hypoxia
8. Bozepinib: A Promising Selective Derivative Targeting Breast Cancer Stem Cells
9. NQO1-Bioactivatable Therapeutics as Radiosensitizers for Cancer Treatment
10. Brachytherapy in Endometrial Cancer
11. Acquisition and Management of Data for Translational Science in Oncology
12. Implications of Radiosensitizer and Radioprotector Factors in Refining the Dose-Volume Constraints and Radiobiological Models


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