"Oxidative Stress: Molecular Mechanisms and Biological Effects" ed. by Volodymyr Lushchak and Halyna M. Semchyshyn

This book covers a wide range of aspects and issues related to the field of oxidative stress. The association between generation and elimination of reactive species and effects of oxidative stress are also addressed, as well as summaries of recent works on the signaling role of reactive species in eukaryotic organisms. The readers will gain an overview of our current understanding of homeostasis of reactive species and cellular processes they are involved in, as well as useful resources for further reading.

Since the discovery of free radicals in biological systems researchers have been highly interested in their interaction with biological molecules. Denoted in 1980, and due to fruitful results and ideas, oxidative stress is now appreciated by both basic and applied scientists as an enhanced steady state level of reactive oxygen species with wide range of biological effects.

Contents
Preface
Section 1 Introduction
1 Introductory Chapter
Section 2 General Aspects of Oxidative Stress
2 Interplay Between Oxidative and Carbonyl Stresses: Molecular Mechanisms, Biological Effects and Therapeutic Strategies of Protection
3 Oxidative and Nitrosative Stresses: Their Role in Health and Disease in Man and Birds
4 Nitric Oxide Synthase and Oxidative Stress: Regulation of Nitric Oxide Synthase
5 Iron, Oxidative Stress and Health
6 Heme Proteins, Heme Oxygenase-1 and Oxidative Stress
7 Assessment of the General Oxidant Status of Individuals in Non-lnvasive Samples
8 Hydrogen: From a Biologically Inert Gas to a Unique Antioxidant
9 Paraoxonase: A New Biochemical Marker of Oxidant-Antioxidant Status in Atherosclerosis
Section 3 Cellular and Molecular Targets
10 Renal Redox Balance and Na+, K+-ATPase Regulation: Role in Physiology and Pathophysiology
11 Effects of Oxidative Stress and Antenatal Corticosteroids on the Pulmonary Expression of Vascular Endothelial Growth Factor (VEGF) and Alveolarization
12 Protection of Mouse Embryonic Stem Cells from Oxidative Stress by Methionine Sulfoxide Reductases
13 Structural and Activity Changes in Renal Betaine Aldehyde Dehydrogenase Caused by Oxidants
Section 4 Reactive Species as Signaling Molecules
14 Signalling Oxidative Stress in Saccharomyces cerevisiae
15 Role of the Yap Family in the Transcriptional Response to Oxidative Stress in Yeasts
16 The Yeast Genes ROX1, IXR1, SKY1 and Their Effect upon Enzymatic Activities Related to Oxidative Stress
17 Complex Regulatory Interplay Between Multidrug Resistance and Oxidative Stress Response in Yeast: The FLR1 Regulatory Network as a Systems Biology Case-Study
18 ROS as Signaling Molecules and Enzymes of Plant Response to Unfavorable Environmental Conditions