"Mitochondrial Diseases" ed. by Eylem Taskin, Celal Guven, Yusuf Sevgiler

This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will be essential for readers who are interested in life sciences, especially in medicine.

Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations.

Contents
1. Mitochondria and Metabolism in Right Heart Failure
2. Mitochondria and Heart Disease
3. Interplay Between Mitochondrial Proteins and Age-Associated Risk of Cardiovascular Diseases
4. Differential Effect of Atpenin A5 on ROS Production from Wild- Type Mitochondrial Complex II in Human Cancer Cells and Normal Cells
5. A New Insight into the Development of Novel Anti-Cancer Drugs that Improve the Expression of Mitochondrial Function-Associated Genes
6. Mitochondria at the Base of Neuronal Innate Immunity in Alzheimer’s and Parkinson’s Diseases
7. Protein Kinases and Regulation of Mitochondrial Function in Ischemia/Reperfusion Injury
8. Mitochondrial Trafficking by Prohibitin-Kinesin-Myosin- Cadherin Complex in the Eye
9. 18 kDa Translocator Protein in Mitochondria-Related Pathology: The Case of Traumatic Brain Injury
10. Hereditary Disorders and Human Mutations of Iron-Sulfur Assembly Genes
11. Nuclear Encoded Mitochondrial Proteins in Metabolite Transport and Oxidation Pathway Connecting Metabolism of Nutrients
12. Pyrethroid Insecticides as the Mitochondrial Dysfunction Inducers
13. Mitochondrial Dysfunction Associated with Doxorubicin
14. Ethanol Consumption Affects Neuronal Function: Role of the Mitochondria
15. Mitochondrial Oxidative Stress and Calcium-Dependent Permeability Transition are Key Players in the Mechanisms of Statins-Associated Side Effects
16. Ketamine Induces Neuroapoptosis in Stem Cell–Derived Developing Human Neurons Possibly through Intracellular Calcium/Mitochondria/microRNA Signaling Pathway
17. Modulation of Mitochondria During Viral Infections
18. Estrogen and Mitochondrial Function in Disease



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