"Hepatocellular Carcinoma: Advances in Diagnosis and Treatment" ed. by Costin Streba, Cristin Constantin Vere, Ion Rogoveanu

Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. This volume is dedicated to recent diagnostic advancements and novel therapeutic solutions.

As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability.

Contents
1. Etiology and Pathogenesis of Hepatocellular Carcinoma
2. Diagnostic Algorithm of Hepatocellular Carcinoma: Classics and Innovations in Radiology and Pathology
3. Innovative Blood Tests for Hepatocellular Carcinoma: Liquid Biopsy and Evaluation of Systemic Inflammatory Reaction
4. Cellular Senescence and Their Role in Liver Metabolism in Health and Disease: Overview and Future Directions
5. The Diagnostic and Prognostic Potential of MicroRNAs for Hepatocellular Carcinoma
6. Oncogenic Secretory Clusterin: A Promising Therapeutic Target for Hepatocellular Carcinoma
7. Minimally Invasive Therapies for Hepatocellular Carcinoma: Mechanisms of Local Control and Systemic Immunologic Response
8. Emerging Targeted Therapies for Treatment of Hepatocellular Carcinoma (HCC)


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