"Glutathione in Health and Disease" ed. by Pinar Erkekoglu, Belma Kocer-Gumusel

This book is mainly focused on reduced glutathione (GSH) in health and disease. The readers will gain qualified scientific knowledge on the diverse functions of GSH, the importance of GSH status against oxidative stress and the interaction between GSH and nervous system-related infections from this book.

Reduced glutathione (GSH) is the most important thiol in living organisms. It is the key component of antioxidant system and serves as a free radical scavenger. There is a cycle of GSH in biological systems and this cycle provides higher intracellular levels of GSH. GSH depletion and apparent oxidative stress may cause toxicity and can affect the general well-being of the organism. GSH was shown to be preventive against aging, cancer, heart disease, infections and dementia.


Contents
1.Introductory Chapter: A General Overview of Glutathione, Glutathione Transport, and Glutathione Applications
2.The Life Evolution on the Sulfur Cycle: From Ancient Elemental Sulfur Reduction and Sulfide Oxidation to the Contemporary Thiol-Redox Challenges
3.The Important Functions of GSH-Dependent Enzyme Glutaredoxin 2 (Grx2)
4.Impact of Oxidative Changes and Possible Effects of Genetics Polymorphisms of Glutathione S-Transferase in Diabetics Patients with Complications
5.The Role of Glutathione in Viral Diseases of the Central Nervous System


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